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Usually, fewer than 5 joints are affected at any one time.

It is differentiated from RA by the presence of distal interphalangeal (DIP) joint involvement, relative asymmetry, an absence of subcutaneous nodules, and a negative test result for rheumatoid factor (RF).

The digits of the hands and feet are usually affected first, with inflammation of the flexor tendon and synovium occurring simultaneously, leading to the typical "sausage" appearance (dactylitis) of the fingers and toes.

The association between psoriasis and arthritis was first made in the mid-19th century, but psoriatic arthritis was not clinically distinguished from rheumatoid arthritis (RA) until the 1960s.

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A large joint, such as the knee, is also commonly involved.

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Psoriatic arthritis is most commonly a seronegative oligoarthritis found in patients with psoriasis, with less common, but characteristic, differentiating features of distal joint involvement and arthritis mutilans.

This was previously thought to be the most common type of psoriatic arthritis.

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